I had a McAfee setup on a pc and it was due to expire. Kept coming up with reminders and although I tried to renew online it just got stuck in a loop - gave up.
I went to my local computer shop to buy a new antivirus setup and ended up buying Panda. No problems over the last year, waiting to see how renewal goes.
I've used Norton in the past. When it was due for renewal there was a newer version so I bought it and tried to load it. It wouldn't load over the old version so I did an uninstall. Some files must have been left behind as the new version just kept coming up with the fact that there was an older version in there. Gave up and set it up on my wife's new laptop.
I've used AVG as an interim setup while configuring other software but prefer the extras that come with some of the brand names. Currently running McAfee Internet Security on a laptop. Slightly long to load but happy with it so far.