Wake vortex is only a problem when aircraft are landing or departing, in en-route we have to use 5 miles anyway so wake vortex doesn't come into it.
Hmmm. Recently I had Britannia B752 on a crossing track with B744. 7NM behind and slower, however, the pilot requested climb for 500ft to “avoid wake turbulence”. It seems that they are affected en-route ass well? By the way, I’m totally confused about wake of B752. I.E. half of the FCAs B752 are category H (clearly displayed on the label) and the other half are M. Very similar situation is with BAL. Any explanation?