I can't honestly say whether or not i've become conditioned over time. If I have, it's been nothing noticeable. Generally speaking, it's not as much of an issue in Airliners as it would be for a charter guy in single engine lighties. In my former days as a parachute pilot, i'd never have any probs clearing the ears and most of the time it happened without my even noticing. When I did get problems was when the drop was aborted and i'd have to descend with passengers which meant a much slower descent than normal in view of passenger comfort. Normal descents at 2000fpm > okay. slower descents at 500 fpm when the rate of change in pressure differential was slow is where i'd have the issues. Given that big jets usually descent alot faster than 500 fpm, not so much of an issue. Unless you've got a cold and yer tubes are totally blocked, that is. Oh, the pain!