Bern Oulli has a good point about the "speed of thought" graph and the "experience" graphs crossing somewhere. That "somewhere" is probably about the late 40s for most people working busy ATC sectors / positions. I remember many seriously struggling beyond age 55.
Shift patterns also take their toll. Typical MMAANNEOOO type cycles are constantly altering the body's circadian rhythms. I believe that there was some limited research undertaken about 20 years ago by Sheffield University regarding the effects of shift patterns on the individual within ATC. Not sure whether the results of that research is in the public domain.
Maintaining job interests is also a vital factor. Changing work tasks can help with this and be a positive experience BUT if it involves relocating then there is considerable stress associated with the move.