Manchester still has a very impresive schedule of point to point flights to Pakistan.
To be honest the other flights were as such not Manchester flights at all and could have transited via anywhere within range that had a long enough runway. A chap from Pakistan to the USA was not bothered where he touched down to re fuel within reason
Looking at the PIA seat availability on the web site before they chenged it there appeard very little Manchester passengers on these flights.
Centre cities