Paxboy
Eastern specialise in routes that enable the business user to do a days work and then return home or to the office the same day, and they charge about the same as the first class (open) return rail fare.
For example, they operate Norwich - Manchester return 3 times daily, at 0645, 1430 and 1730, the flight takes 40 minutes. The road journey is at least 4 and a half hours, the rail journey is roughly the same. The return air fare is around £190, the return frist class open rail fare is £170 and takes 4 hours longer.
The vast majority of other routes are operated on the same basis.
Eastern took on many routes which were previously operated by British Airways subsidaries within the UK, and have proved to be very successful.
They've not expanded their fleet too quickly, the EMB135/SAAB2000/Jetstream 41s are ideal for the services they operate on.
They aren't the cheapest, but it depends on how much your time is worth, and in this respect they offer an extremely efficient service which I have used on many occasions.
At several airports they run head to head with low cost operators to the same destinations, but haven't seen a major loss of revenue.
Their business model is one that would work very well elsewhere, it really depends on whether you can find the backing to keep going through the first two years whilst building up the trade.