1. climb to MSA asap, and then fly quadrantal rule
2. turn on pitot heat and any other equipment necessary
3. upgrade service to at least RIS
4. check OAT/surfaces to ensure no icing occuring
5. if you are planning on flying IMC without de-ice then ensure freezing level is above MSA. if unplanned then you need an MSA with temp above zero or you have a problem....