An outboard engine will always be more critical than an inboard because the yawing moment is greater, thus greater trim drag.
(If a tri-jet loses a center engine, for example, there is no yaw moment.)
Now that I think about it, if a DC-10 or MD-11 loses #2 (with its thrust line well above the Cd), there must be a noticeable nose-up reaction, but still no yaw.