Use what the ICAO document says. i.e. don't use town names in the route.
If you want to help local ATC then in other information use a remark to explain where the navaid range/bearings are referring to.
e.g.;
RMK/ Turnpoints ABC090012 (Smallville) DEF330050 (nice town)
Then your flight plan will be correctly compiled and anyone reading the plan can (if they know the region) see where you are routing without having to plot your route.
Regards,
DFC