Vibro-acoustic Disease. Turns yer soft tissue to cartilage and makes you permanently grumpy. Shortens the life span and accelerates the arthosclerosis, permanent mood swings, mostly to the nasty side.
We are just starting to fund a project with one of our 'flying Doctors' on this subject. Seems the worst offenders (for our fleet) are the A310's at low altitudes and high speed. Slowing down diminishes the effect on the human body. Our doc mentioned that's the reason why one feels like a spent cartridge coming off a day's work whereas spending the same amount of time as an earthbound working stiff leaves one somewhat useful for other carnal pursuits.

With that, I am off to enjoy my day of rest