Well let's look at that. In the group of aircraft that are involved in multi-crew air transport operations, we have low-performance aircraft (like the B1900D), and medium-performance aircraft (B737 etc) and high-performance aircraft (GV etc).
So tell me which is safer... a tired crew on their sixth sector, in crappy wx all day, doing a hand-flown NDB/DME approach in a B1900, or a 737 crew, with full autoflight and flying a coupled approach? Especially considering the likely experience levels of each crew.
But no, hand-flying in bad wx makes men out of us... only a girl uses an autopilot... etc etc etc