Guess there is no point in reintroducing the idea of a winglets 737-700 being tried out on the CO EWR-BRS? You'd get your full load that way, if not the yield?
What ETOPS would be needed for such a flight? 120 mins or 138 mins?
As for long hauling in a 737 Astraeus in the UK used to go direct to Equitoreal Guinea in west Africa and Copa from Panama go all the way directly to Buenos Aires so 7 hour flights are just possible with the little extra for go around and and a nearby alternate?
Better still, combine the CO BRS as a triangle with ORK and keep with the 757! Only joking!