RW-1,
It is true, the FBW controls on Comanche use a twist of the cyclic to control yaw. The stick is a sort of joystick from a video game, with triplex sensors to pick up cyclic, collective and yaw controls. There is also an electric collective stick for the left hand.
Regarding the question about left handed flying, when I was in flight school, I flew the OH-13E and G (basically Bell 47's). From the left seat of that aircraft, it was easy to grasp the right seat collective with the right hand and the cyclic with the left. I did three traffic patterns with friends watching, on a bet, with reversed hands. The only issue I had was working the twist grip throttle as I raised the collective.