I think you wil find that windows are considered part of the structure of the aircraft, Cpt Stable. A failure of window would probably start as a crack and get progressively worse until it lost all its structural integrity, then it could blow out but this is highly unlikely. Even if a hole the size of the window opened it would not cause explosive decrompession, merely a fairly steady climb rate/rapid decompression. I would not like to be sitting near it though!
If the damage is caused by a bomb and perhaps occured near the tail area then a slow speed decent might be advisable in which case it would be done at Max gear extension/flight with gear extended speed. Speed brakes would have little effect on the tail area unless your particular type has a significant buffet with them extended. The rates of decent in this configuration are not too dissimilar to the MMO, they just feel that way!