I have done this trip a few times. MY preferred routing is EGSC WCO then to Bembrridge direct but you really need a GPS to track accurately from WCO and good VFR to stay clear of Lasham gliding etc. During the week , Benson and Farnborough will assist.
A slightly more entertaining alternative is EGSC BPK BNN but that takes you closer to the Wycome choke point.
As a refinement to the latter, if you are really bored you can ask for a transit through the Luton zone but you will have to sound confident on the R/T, give accurate position reports and be lucky with ATC and their traffic at the time. In any case, you save very little time.