I have gotten fed up with it too. McAfee works OK but..............Mailwasher works OK but.................and others seem to work well but...............what I have done, because most spam comes in on one addy only. Is to block it in OE by changing the server - anything in fact.
Then every few days I go to
www.mail2web.com and type in the addy you blanked and your password, and there you are - loads and loads of spam. You can check it or kill it before it gets into your pooter. Nice and clean. Haven't had any spam on that addy for weeks - at least on my pooter. Bliss, absolute bliss!