Have you run spybot in safe mode? I had serious I.E problems, in that it wouldn't open etc etc. This worked for me ( i had a horrible something lurking). And seriously suggest your friend gets Mozilla FireFox!
Much more secure, as easier to browse - can install things such as tabbed browsing in one window.
I'm not very good at Hijack this. Infact I don't have a clue....But the guys on CastleCops (PC Forum) are and have a special
Hijack This part of the
forum
IE is very unsecure. Since I have stopped using it I haven't had a single problem.
Apologies about the skin on my Mozilla, my brother 'Pimped' my Firefox 