The worst seats aren't necessarily the ones at the rear. If it's a free choice, heading straight down the back often means you get your choice of aisle or window, its easier to get your stuff loaded into the overhead locker, and families and general undesirables so often seem to want to be as close to the front as possible.
Straight down the back, plonk in a window seat (choice dependent upon desired on-route viewing) in the penultimate row (the back seats are pretty cramped), unless it's full it's very rare for anyone to take the middle seat so, in the cruise, I can lift the armrest and plonk the laptop on the middle seat tray table, avoiding that 'hunched-up' experience.
And on arrival in UK home airport of BRS it's straight off the via the rear steps
Cheers,
Rich.