Don't see why it can't be done. The fundamentals don't change any from singles to twins (power, attitude, trim, lookout etc...), and the assymetric handling aspect doesn't require a huge amount of time to grasp. Depending on the type you might be flying, the speeds, power and complexity are not exactly a quantum leap from most light singles.
6 hours with your experience should be a doddle, especially if you are looking at VFR flying afterwards.