Depends on the sim!
The 'K' sim I remember was very good at teaching tech and procedures training but I never want to do another IRT in the d@mn thing! The newer ZFT sims, including the J's and I would expect the A400's, can reproduce the characteristics to complete the vast majority of multi-engine flying accurately and safely.
There is no need to waste fuel, flight time, noise complaints, engineering and extra crew by operating a real aircraft for most training tasks just because older aircraft (and pilots) have always done it that way!