Binoculars,
By booting in Safe Mode, windows loads with the bare minimum so you have a better chance of removing nasties from your system. With Win9x you have the chance of booting with a floppy and remove anything in DOS Mode.
Take Care,
Richard
P.S. If your computer is running slow and it speeds up when you stop the REALSCHED.EXE the remove it, if it does not change, leave it.