They are tough - no doubt about it. Put it into perspective though. If you want an enjoyable job that pays big bucks there are downsides too.
In addition any job these days that pays anything close to what I'm on involves long unsociable hours. Ask my partner who earns the same as me in a deskjob, who regularly leaves the office at 7pm and goes in on a Saturday to finish her weeks work.
Best post on this thread is scameron77's. Sums it up well.
But then climbing out of Linate at 6am with the morning sun on the Alps is a memory that will stay with me forever and I'm sure the view of an excel spreadsheet will stay with my partner forever but not for the same reasons!!!!!