Hey flyndad, tons of Twin Otter jobs especially up north. One that I can think of is Kenn Borek Air LTD. They own over 34 Twin Otters and I believe they hire F/O's with only 300 HRS! Some operators may require more. And if you have your float endorsement as well they may send you to the Maldives for a season which is an awesome place to fly. If you are interested:
Contact
Mr. Sean Loutitt, Chief Pilot
Fax: (403) 250-6908
Apply by Faxing your resume.
Good luck!