Thanks everyone.
I am just starting very preliminary planning. I most likely will fly US Airways to LGW, CDG or FRA, then purchase tickets onwards (assuming US Airways is still flying -- the company just re-entered bankruptcy today).
Not absolutely sure yet where we will go, but we have been trying to get to Dubrovnik for about two years now, and it never works out. I may surprise my wife and plan a vacation there sometime next spring or summer.