Hi Xnr
Any twin has a certain capacity with 1 engine out. From the flight manual you can calculate what your weight should be to achieve single engine performance. This then becomes the weight you use from that helipad to give full engine out capability.
For example when we did marine pilot transfers to LNG tankers in a S76A++, we had to have full single engine capability from beginning to end. Sikorsky recommended an approach & take technique & weight which we stuck to. We had 2 pilots, about 500-600 lbs fuel, sometimes less on very hot windless days, and took 1 or 2 marine pilots. At the weights we used, I could have done the whole flight on 1 engine.
So it just depends what rules exist in your area and then adjust the weight accordingly.