Recently in Aircraft Commerce (April/May 2004) there was a 5-page analysis of ultra-longhaul routes and 345/7E7. Interesting reading. Basic summary was the idea of "long-thin routes" has failed at SQ and EK with A345. It works, but there is no commercial success becuase there is a lack of point-to-point passengers. A345 became a prestigious and expensive toy, but not a yield improving tool. Furthermore there is literally just a few other routes where anyone can deploy A345 without facing constant losses and no perspectives.
Article also basically says it is likely 7E7 would be just a replacement for 767s on existing routes, not a new routes explorer.