I think it would be a shame from a customer viewpoint to see the Zurich route axed, especially as they are the only major competition to the one world alliance(BA & Swiss) between London and Zurich, although I have heard that EUJet are doing Zurich from Manston, which at least provides an alternative.
I've never understood why Zurich is so much more expensive to fly to than Geneva, perhaps someone can shed light on this?
Perhaps other domestic routes from NEMA will go (Edinburgh) and maybe a tweaking of routes from the other regional bases to BCN.