The most likely thing I can see as happening over at BHX, is either for the existing operators like Lufthansa, Air France or Swiss to fill in the void on the routes that duo were operating, or for other carriers to expand their operations at BHX or EMA.
Perhaps MyTravelLite will go back to their original business plan of providing a no-frills alternative to Birmingham, as opposed to Stansted and launch some business routes - (although it seems all attempts at this have failed!)
EasyJet have already stated their intention to launch CGN, they serve GVA - whose to say they wont add a Berlin flight - especially as Berlin is a big up & coming base at U2.
Also, Ryanair have said they will grow their operations from EMA - why not add Bergamo, Torp & Skavsta.