I have some time in a couple of 210s and P210s, they are great aircraft and if you are up to speed they are safe.
The accident reports seem to suggest that they have more crashes than most light singles, but most crashes are down to the drivers not being trained properly.
If you move from a 182 you are moving from just over 2 miles per min to 3 miles per min in a 210 and they also require a lot more time to slow down.
If you do buy one go to the states and learn to fly it properly with high time 210 instructors not with your local PA 28 instructor in the UK (no offence meant to our instructors)
R L Collins of Flying mag in the US has had a 210 for over 20 years so read some of his thoughts on the Flyingmag.com site.
Also read
this
Tony R