You don't see any A340's being operated by US carriers. Boeing thinks that, if it's not going to happen there, it's not going to happen anywhere else but, this philosophy is obviously flawed. The 340 has made it's mark in the world and I am sure the 380 will do the same thing. Success favours the brave! and I think the 380 will endow it's operators with a sense of awe, not seen since the days of the Drooped Nosed Beast from Bristol.
Lets hope that this goliath will appeal to the madding crowd and not just the financial elite.