It is not unheard of in airline ops, to ever so once in a while, get a trim sheet which is grossly out.
So if the fltcrew is not too preoccupied,they should be able to detect it from familiarity with the numbers.
A Singapore 747 suffered a major tailstrike on rotation,when the numbers were out by a 100 tons.
So moral of the story---stay focused folks !
Happy Landings!