Weather determines your route and progress.
Three routes available to you depending upon your fuel range.
The Coast, the Trench, or the Alcan...pick your poison.
Have done all three. The Alcan route is the most dependable with a nice road to follow and places to stop along the way. The weather has to get really....really bad to force you to stop.
Laird River Hot Springs is a must place to visit.
The trench runs from White Horse to Prince George with not much in-between. The Trench can be a point of no return flight should the weather turn on you.
Then there is the Coast route which can be very pretty or really bad weather.
Carry your survival gear, shotgun and fly your flight plan route so if you have to land out folks know where to come looking for you.