I refer you back to the discussion in 994…..
Seems likely to be a vibration problem once ullage levels fall below a certain level leading to cavitation and pipe failure leading to erratic engine surges until the nozzle then complete engine blows.
Presumably they’ll have to find some way to damp the vibrations.
Interesting it didn’t happen to the earlier version of the Starship though - might be a simple reversion to the original methane pipe design.