Yes, I appreciate starting the leg on a Ryanair flight wouldn't characterise LCA as a hub in the conventional sense, but I know friends who have done self-connect routings through places like Venice on to Tel Aviv. I don't know many from the Bournemouth/Southampton area that would even consider using BRS for a hub flight, let alone a direct flight when they could head towards the London airports in the same travel time (or less).
As for Southampton do people does anyone ever use it as the start of a hub flight these days?