Small world-I used to fly CL 44s for Wrangler Aviation (one of them was an ex TM bird). In my 7 years there I did about 4 three engine takeoffs and ferry flights. On three it would fly about 2000 feet lower and about 10-15 knots slower. On a US certificate were were limited to no freight and no passengers. FWIW-it flew a lot better with about 10,000 pounds of "ballast" on the airplane.
As BSD stated all training was done in the aircraft-three engine stall does at night will get your attention, but again with no cargo on board the airplane was almost overpowered.