From the video it looks like the booster developed a leak and had a RUD during the turn back. Could be from damage during the hot separation, in which case they’ll have to modify the sequence and/or strengthen the dome on the booster for the next launch.
Starship lost contact almost simultaneously with the planned SeCO and could be a problem with the engine shutdowns and possible course deviation triggering the inflight termination system autonomously. They’ll have to parse the data to identify that, but it doesn’t seem like a hardware problem.
Launch site and OLM seem undamaged, so the deluge system seems to have worked perfectly and no issues for future launches under the current licence.
Next launch( timing will probably be dictated by any hardware changes to the booster.
But it was a beautiful launch.