Never had an issue with PAX location for a Loadsheet. I did need to get an accurate count of children and infants once in order to get the last pallet on a DC-10 to HNL, but that was a weight issue, not balance.
As for the computer putting the Trim “on the edge”… I would imagine you’d want to get that software patched pretty quick! Besides, there’s a couple of envelopes that you work to & the Airbus or Boeing limit is not the default! 🙄