Aerotoxicity certainly was a factor in the deaths of a few colleagues. However, a lot of us flew the 146 with no ill effects. Maybe there is/was a genetic factor. Regarding longevity, I retired medically just before my 58th birthday. I'm now 76, spending a lot of time volunteering in various capacities, and feeling good. The only drawback is that my brain thinks I'm 26, and wants to do things the 76 year-old body objects to!!