How far below MSA?
The Minimum Sector Altitude (MSA) is the lowest altitude which may be used which will provide a minimum clearance of 300 m (1 000 ft) above all objects located in the area contained within a sector of a circle of 46 km (25 NM) radius centred on a radio aid to navigation. (ICAO PANS-OPS/I - definitions)
Are you surrounded by terrain a la Quito?
Terrain on one side only like a shoreline airport?
You can’t be that far below MSA otherwise you’d already be close to minimums in which case your question does not apply.
Climb and turn in the direction of the lowest terrain.