Did not see this one on similar threads before (coming via FullWings at #40)
Even for the most basic case with remotely-piloted, autonomous in an emergency, single-pilot supervised cruise phase mode, there would need to be a toilet inside the secure flightdeck perimeter.
Althought I understand the available P2F Airbus conversion already may have that.
Job-wise what scares me more is ranges (=flight-times) that'd allow the full 'basic-rest' to be taken on-board, closed loop. Tongue in cheek? Knowing what the 'west' could come up with, looking at the ideas that may spring up from the SE Asia region makes you shiver.