Class E effect at low altitude without supporting controlled towers to coordinate traffic you have to delay all departures until departing traffic has reached a minimum safe altitude. And all arriving traffic gets the same treatment. Especially if radar is not available to ground level they have to place large restrictions on movement and 20nm separation etc. Good examples is other class E entries at 8.5/12.5 where radar is not available you will not get clearance until radar identified if there is any traffic inbound within 100nm. The whole point of class E is to coordinate IFR en-route traffic, it only provides traffic on known VFR. VFR are uncontrolled so class E will not effect them at all other than they carry a transponder above 5000ft. At some places I've had aircraft departing in opposite directions and ATS will still not clear you until both are identified if you are the second aircraft.