I think what flaps8 said is right.
You have to look at the demographic of the two crew cockpit actually flying.
Some work and some do not.
2 very experienced skippers can worsen situations.
It is generally a ticking time bomb!
Swissair is a good example of that. They were to busy arguing about a course of action to tackle the emergency than actually doing it. Even declaring PF and PNF can not sort the situation out completely.
I think many airlines have taken note of this and I think they have seen that there is no real cure either. Just rostering adjustments.
Don't get me wrong! I am not saying single crew is better, I am just trying to point out that many multi crew situations can make things worse!