There's one line of thought (I'm reading elsewhere) that with the US space effort being increasingly commercialised and also looking increasingly beyond Low Earth Orbit the ISS's days may be numbered as funding is diverted into more glamorous projects..question then is who gets left to foot the bill/make the effort to turn the lights out/de-orbit the thing safely....
Whatever the Russians are up to they are constructing at least one new module, supposedly for the ISS but could it be repurposed for use as start of a standalone Russian only station (unlikely - funds) or a joint effort with the Chinese and/or others?
The new module visible at about 5:40