Had first dose of AZ couple of days ago. That evening felt pretty unwell with flu symptoms - fever / chills; body pain; stiff neck; sweats and a pretty bad headache. Fine by lunchtime the following day.
I would certainly have been entirely unfit to fly (i did not even feel fit to drive my car).
Everyone is different but i'd factor the possibility that you could feel pretty rubbish for a couple of days into your planning.
Be safe.
OH