B-29 was pressurised and the hemispherical nose is the optimum shape to withstand the pressure within the cylindrical fuselage.
Almost all other pressurised aircraft have some sort of pointy-bit in front of their hemispherical part (pressure bulkhead) which disguises the gas-cylinder shape so obvious in the B-29.
I had an interesting look around Lucky Lady, the “ around the world” B-50 fuselage at Chino. Possible to stand in the bomb bay and look into the cockpit through the hatch in the rear cockpit pressure bulkhead where the tube connecting cockpit to the rear pressure bay had been.
Aesthetically? A draw for me.
B-17 still has something of the aviation golden-age about it. Style, glamour, comfort etc.
B-29 / B-50 looks every inch the modern weapon without compromise that it was.