WHBM
"Well that's certainly what Boeing marketing implied, with their guff about "avoiding the crowds at the hub". Maybe they should have said "Avoiding the crowds at one of the two hubs you might have used if your journey is one of the few that connects at two hubs, but otherwise we're going to sell the aircraft to be used on routes replacing the 777 or even the 747, like the one that moaner WHBM on PPRuNe took LHR-IAD, which used to be a 747 route for the previous 50 years".
Missing out any stop on a 3+ leg route isn't to be sniffed at.
BA, for example, were certainly using the 787 (pre-Covid) on several routes that would previously have required a transfer over an intermediate hub. The fact that EDI or GLA traffic would still need a domestic transfer over LHR doesn't invalidate the argument.
I only have vague recollections of the Boeing marketing campaign, but I'm pretty sure it didn't include an assertion that "you'll never see this aircraft at any hub airport".