custardpsc
We won't know until we see the specific mutation. Think of the virus as having a lock (spike protein), and your immune system has to find a key (antibodies). What the vaccine has done is given your immune system a head start in finding the correct key. A mutation in the virus can change any number of things. If the mutation changes the lock on the virus, the key that the vaccine delivered may become less effective if shape of the lock changes significantly. The combinations are practically endless.