I'm left handed, but clearly I have to right hands, or left hands depending on the way you see it. It's been extremely difficult for me to learn to fly a glider, an aeroplane, and a helicopter, but hard work can compensate poor natural skill.
I have the kneeboard on the right knee. When I fly aeroplanes, I cannot write the new frequency while acknowledging it. Just a slight workload increase to cope with.
When I fly gliders I don't care. So many other things to cope with...
When I fly helicopters, I don't have a kneeboard.