Would you prefer an afternoon of headache and fatigue or getting infected, quarantined for two weeks, risking infecting an elderly family member or coworker? To me, the choice is rather obvious, but perhaps the concept of the lesser evil is as subjective as everything in life. The important bit is having good certainty that there will be no long-term damaging side effects. As long as this is assured, a day or two of mild to moderate discomfort is a tiny price to pay.