If you go to Paris or Frankfurt both have reduced freight, Air France have basically pulled out of pure freight as have BA and Lufthansa Cargo is much smaller,
US freight operators have reduced. FedEx is a hub operator with Paris and to a smaller facility at STN and the same idea with UPS and DHL, most of the other freight is military.
There is no-way Manchester could handle the likes of Fed-ex, UPS etc because they have feeder services, have you seen how many flights go to EMA
to connect per night and of course they have virtually no pax flights